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Publications de la R&D d'Unicancer

2018

Letrozole and palbociclib versus chemotherapy as neoadjuvant therapy of high-risk luminal breast cancer.

P. Cottu et al, Ann Oncol. 2018 Dec 1;29(12):2334-2340. doi: 10.1093/annonc/mdy448.

2018

The 21-gene Recurrence Score® assay predicts distant recurrence in lymph node-positive, hormone receptor-positive, breast cancer patients treated with adjuvant sequential epirubicin- and docetaxel-based or epirubicin-based chemotherapy (PACS-01 Trial)

F. Penault-Llorca et al, BMC Cancer. 2018 May 4;18(1):526. doi: 10.1186/s12885-018-4331-8.

2018

UCBG 2-08: 5-year efficacy results from the UNICANCER-PACS08 randomised phase III trial of adjuvant treatment with FEC100 and then either docetaxel or ixabepilone in patients with early-stage, poor prognosis breast cancer.

M. Campone et al, Eur J Cancer. 2018 Sep 26;103:184-194.

2018

FOLFIRINOX or Gemcitabine as Adjuvant Therapy for Pancreatic Cancer.

T. Conroy et al, N Engl J Med. 2018 Dec 20;379(25):2395-2406. doi: 10.1056/NEJMoa1809775.

2018

Rationale and Design of the IROCAS Study: Multicenter, International, Randomized Phase 3 Trial Comparing Adjuvant Modified (m) FOLFIRINOX to mFOLFOX6 in Patients With High-Risk Stage III (pT4 and/or N2) Colon Cancer-A UNICANCER GI-PRODIGE Trial.

J. Bennouna et al, Clin Colorectal Cancer. 2018 Oct 19. doi: 10.1016/j.clcc.2018.09.011.

2018

Prognostic factors of colostomy free survival in patients presenting with locally advanced anal canal carcinoma: A pooled analysis of two prospective trials (KANAL 2 and ACCORD 03).

JC Faivre et al, Radiother Oncol. 2018 Aug 29. doi: 10.1016/j.radonc.2018.08.008

2018

High-Dose Chemotherapy and Blood Autologous Stem-Cell Rescue Compared With Standard Chemotherapy in Localized High-Risk Ewing Sarcoma: Results of Euro-E.W.I.N.G.99 and Ewing-2008

J. Whelan et al, Journal of Clinical Oncology 36, no. 31 (November 1 2018) 3110-3119.doi: 10.1200/JCO.2018.78.2516

2018

Ewing's Sarcoma of the Head and Neck: Margins are not just for surgeons.

J. Bouaoud et al, Cancer Med. 2018 Dec;7(12):5879-5888. doi: 10.1002/cam4.1801. Epub 2018 Nov 17

2018

A Pharmacokinetic and Pharmacogenetic Analysis of Osteosarcoma Patients Treated With High-Dose Methotrexate: Data From the OS2006/Sarcoma-09 Trial.

G. Lui et al, J Clin Pharmacol. 2018 Dec;58(12):1541-1549. doi: 10.1002/jcph.1252. Epub 2018 May 23.

2018

Efficacy and safety of regorafenib in adult patients with metastatic osteosarcoma: a non-comparative, randomised, double-blind, placebo-controlled, phase 2 study

F. duffaud et al, Lancet Oncol. 2019 Jan;20(1):120-133. doi: 10.1016/S1470-2045(18)30742-3. Epub 2018 Nov 23.